ABSTRACT
Background: Documentations of the effect of treatment on the quality of life of keloid patients are few. This study assessedimprovement in quality-of-lifefollowing keloid treatment. In addition, to assess which of the offered four modalities of treatment improved quality of life more.Methods:Thisquasi-experimentalstudy was conducted on 32 adults who had treatment for keloid disease in the clinic from February 2019 to January 2020. This was part of a comparative study of four different modalities of keloid treatment. The quality of life was assessed before and after treatment using the Dermatology Life Quality Index questionnaire (DLQI). Data was analyzed using SPSS version 23.0Results:Quality of life significantly improved after treatment with the mean ± SD DLQI score improving from 7.75 ± 6.15 to 4.16 ± 4.93, p=0.001. Quality of life before treatment was impaired in 93.7% and improved to 65.6%. Before treatment, 2 patients had no QOLimpairment but this improved to 11 patients after treatment. Prior to treatment, severely impaired QOLwas in recorded 28.1% of thepatient's and in 9.4% after treatment. Quality of life improved more in patients who had the combined intralesional triamcinolone acetonide and 5-flourouracil treatment. Significant improvement in the DLQI items of symptomatology, embarrassment, social activity and choice of clothing was noted.Conclusion:Treatment of keloid improves quality of life and this is dependent on the modality of treatment. The items of quality of life improved include; embarrassment, choice of clothing, interference with socialactivities, symptoms of pain and pruritus.
Subject(s)
Humans , Male , Female , Quality of Life , Signs and Symptoms , Dermatology , Keloid , DiagnosisABSTRACT
Background: Literature specifically documenting clinical characteristics of childhood vitiligo are few when compared to the documentation in adults in Nigeria. This study aims to document the clinical characteristics of childhood vitiligo.Methods: This was a retrospective cross-sectional study of 35 children diagnosed to have vitiligo from January of 2005 to December of 2010 at the dermatology outpatient clinic of the University College Hospital, (UCH) Ibadan. A proforma was used to extract socio-demographic variables and clinical features from the chats. Ethical clearance for the study was given by the research and ethics committee of the hospital.Results: Over the 5 year period, 35 out of 264 children were diagnosed to have vitiligo giving an incidence of 13.3 %. The children were made up of 34.3% males and 65.7% females. At presentation, 71.4% of the children were aged 0-10 years. In 80% of the children, age at onset of vitiligo was before age 10 years especially at age 6-10 years. The commonest area of onset was the face/scalp (51.4%) and the commonest type of vitiligo was segmental. Severity of vitiligo was <9% in 97.1% of cases. Vitiligo was in an exposed part of the body in 88.6% of the children. Only females had the genitalia as area of onset of vitiligo.Conclusions: Childhood vitiligo is mainly segmental, re-pigments well and occurs more in females. Only females have the genital area as the area of onset.
ABSTRACT
A 33-year-old male was treated with isotretinoin (20mg daily) for hidradenitis suppurativa. After 6 weeks on the medication, he developed symmetrical erythematous tense blisters on the lower legs. Report of biopsy done was of intraepidermal blisters with superficial dermal lymphohistiocytic infitrates. He was commenced on oral prednisolone 30mg daily and Isotretinoin was withdrawn. The blisters resolved over a 2week period. The lesions of hidradenitis suppurativa were noticed to have improved with the short course of isotretionoin.